Products
Para-aminosalicylate sodium
Pharmacotherapeutic group
Antituberculosis drugInternational name
Aminosalicylic acidDosage form
Coated granulesPara-aminosalicylic acid and its sodium salt (PAS) show a bacteriostatic activity against Mycobacterium tuberculosis. PAS is inferior to isoniazid and streptomycin in terms of its tuberculostatic activity, so it is used in combinations with other more potent anti-TB drugs (isoniazid or isonicotinic acid hydrazide derivatives, cycloserine, kanamycin, etc). Combination therapy delays emergence of drug resistance and mutually potentiates effects of co-administered drugs.